Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | STAT5B | P51692 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677666 | 0.81 | ESR1 (0.42) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22686925 | 0.80 | MRGPRX4 (0.40) | MRGPRX4TSHRPTGER1ALOX15HMGB1 | |
| SCHEMBL13656744 | 0.79 | NR1D1 (0.40) | TSHR | |
| SCHEMBL18172845 | 0.77 | TSHR (0.40) | TSHRALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL6676029 | 0.77 | TDP1 (0.46) | TSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1626936 | 0.75 | TSHR (0.40) | TSHRALDH1A1KDM4EHPGD | |
| SCHEMBL28615799 | 0.75 | PTPRC (0.35) | STAT5B | |
| SCHEMBL8886804 | 0.75 | AKT1 (0.33) | HMGB1STAT5B | |
| SCHEMBL12407025 | 0.75 | MRGPRX4 (0.47) | MRGPRX4TSHRALOX15ALDH1A1KDM4E | |
| SCHEMBL1845414 | 0.74 | AKR1B1 (0.43) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739163-A | ANTICOAGULANTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5523302-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-06-04 | — | — | US | disclosed |