Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | STAT5B | P51692 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.30 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958553 | 0.76 | HMGB1 (0.41) | CYP4F2CYP4A11CFDHMGB1CXCL12 | |
| SCHEMBL7385138 | 0.75 | MRGPRX4 (0.42) | STAT5BHMGB1 | |
| SCHEMBL24821303 | 0.74 | GRM2 (0.39) | AKT1GRM2CYP4F2CYP4A11 | |
| SCHEMBL4396244 | 0.73 | GRM2 (0.41) | AKT1GRM2 | |
| SCHEMBL29077699 | 0.72 | GLS (0.41) | AKT1STAT5B | |
| SCHEMBL19153416 | 0.72 | AKT1 (0.43) | AKT1GRM2CYP4F2CYP4A11 | |
| SCHEMBL13234266 | 0.72 | GRM2 (0.41) | AKT1GRM2CYP4F2CYP4A11 | |
| SCHEMBL8635430 | 0.72 | AKT1 (0.44) | AKT1GRM2CYP4F2CYP4A11 | |
| SCHEMBL18173003 | 0.71 | AKT1 (0.43) | AKT1GRM2 | |
| SCHEMBL18047659 | 0.69 | GRM2 (0.39) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599926-A | PEPTIDE BONDING PROPERTIES MAKE IT USEFUL IN PURIFICATION PROCESSES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| US-5571911-A | CYCLIC OLIGOPEPTIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1995020590-A1 | ENANTIOSELECTIVE RECEPTORS FOR AMINO ACID DERIVATIVES, AND OTHER COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-08-03 | — | — | WO | disclosed |
| US-5342934-A | For resolution, purification | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1994-08-30 | — | — | US | disclosed |
| WO-1994000455-A1 | ENANTIOSELECTIVE RECEPTOR FOR AMINO ACID DERIVATIVES, AND OTHER COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1994-01-06 | — | — | WO | disclosed |