Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | DRD3 | P35462 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940157 | 0.82 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL16569372 | 0.80 | ALDH1A1 (0.39) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL20764812 | 0.80 | ALDH1A1 (0.39) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL29397580 | 0.77 | USP2 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL4635104 | 0.76 | MME (0.41) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL29400724 | 0.76 | NAAA (0.41) | MEN1KMT2A | |
| SCHEMBL4633169 | 0.76 | MME (0.42) | MEN1KMT2ASLC6A3HTT | |
| SCHEMBL4633172 | 0.76 | MME (0.42) | MEN1KMT2ASLC6A3HTT | |
| SCHEMBL10704937 | 0.75 | NAAA (0.43) | MEN1KMT2A | |
| SCHEMBL29870434 | 0.75 | NAAA (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019386-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998038179-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |