Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKLR | P30613 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393934 | 0.89 | F2 (0.49) | F2ALDH1A1MAPTTP53POLB | |
| SCHEMBL7395993 | 0.89 | ALDH1A1 (0.37) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7392529 | 0.82 | TSHR (0.40) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7395518 | 0.81 | F2 (0.38) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7391715 | 0.78 | F2 (0.51) | F2ALDH1A1MAPTTP53POLB | |
| SCHEMBL6636191 | 0.78 | F2 (0.68) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7394301 | 0.77 | F2 (0.50) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7392579 | 0.77 | F2 (0.45) | F2ALDH1A1MAPTTP53POLB | |
| SCHEMBL7392629 | 0.77 | F2 (0.40) | F2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL7388035 | 0.76 | TSHR (0.38) | F2ALDH1A1TSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM ZENTRALE GMBH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008014-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-17 | — | — | WO | disclosed |