Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FABP1 | P07148 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392529 | 0.94 | TSHR (0.40) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL7393575 | 0.85 | F2 (0.43) | TSHRALDH1A1MAPTF2FNTA | |
| SCHEMBL7389790 | 0.80 | CHEK1 (0.37) | TSHRALDH1A1MAPTCHEK1KDM4E | |
| SCHEMBL7385266 | 0.76 | F2 (0.39) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL6634546 | 0.76 | F2 (0.47) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL6635031 | 0.75 | F2 (0.45) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL7393934 | 0.75 | F2 (0.49) | ALDH1A1MAPTF2TP53POLB | |
| SCHEMBL6635727 | 0.75 | F2 (0.49) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL6633463 | 0.75 | F2 (0.45) | TSHRGAAALDH1A1MAPTF2 | |
| SCHEMBL6637732 | 0.74 | F2 (0.43) | TSHRGAAALDH1A1MAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM ZENTRALE GMBH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008014-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-17 | — | — | WO | disclosed |