Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.59 |
| ▸ | CDC7 | O00311 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767485 | 0.79 | ALDH1A1 (0.56) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL11996133 | 0.77 | KDM4E (0.61) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL1673943 | 0.76 | GSK3B (0.52) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL497227 | 0.76 | GSK3B (0.52) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL12207381 | 0.76 | GSK3B (0.52) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL3825102 | 0.76 | GSK3B (0.44) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| Hydrochloric Acid SCHEMBL3819113 | 0.75 | GSK3B (0.51) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL4493177 | 0.74 | BACE1 (0.63) | GSK3BALDH1A1 | |
| SCHEMBL11904954 | 0.74 | GSK3B (0.78) | GSK3BCDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL1652089 | 0.74 | GSK3B (0.63) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070683-A2 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-09-27 | — | — | WO | disclosed |