Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384945 | 0.81 | ALDH1A1 (0.47) | NQO2ALDH1A1TSHRHKDC1CYP2C19 | |
| SCHEMBL22667212 | 0.81 | MEN1 (0.54) | MEN1KMT2ATP53NQO2ALDH1A1 | |
| SCHEMBL7384499 | 0.80 | NQO2 (0.48) | MEN1KMT2ANQO2ALDH1A1TDP2 | |
| SCHEMBL7383673 | 0.80 | CDC25A (0.48) | MEN1KMT2ANQO2ALDH1A1MAPT | |
| SCHEMBL30344976 | 0.76 | MEN1 (0.49) | MEN1KMT2ATP53NQO2ALDH1A1 | |
| SCHEMBL7387647 | 0.74 | KDM4C (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24148135 | 0.72 | MEN1 (0.57) | MEN1KMT2ATP53ALDH1A1TSHR | |
| SCHEMBL32675619 | 0.72 | MEN1 (0.54) | MEN1KMT2ATP53ALDH1A1TSHR | |
| SCHEMBL9685018 | 0.71 | AKR1B1 (0.55) | MEN1KMT2ATP53NQO2ALDH1A1 | |
| SCHEMBL1130214 | 0.68 | CDC25A (0.57) | MEN1KMT2ATP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490263-A1 | Alpha-oxoacetamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |