Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384945 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8536351 | 0.80 | MEN1 (0.51) | KDM4CMEN1KMT2ASRD5A2MAOB | |
| SCHEMBL7383673 | 0.76 | CDC25A (0.48) | MEN1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL7385654 | 0.74 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6295953 | 0.70 | MAOB (0.49) | KDM4CMEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL9893322 | 0.68 | MEN1 (0.46) | KDM4CMEN1KMT2ASRD5A2MAOB | |
| SCHEMBL13401829 | 0.68 | HDAC3 (0.52) | KDM4CMEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL3054083 | 0.68 | PLA2G4B (0.64) | MEN1KMT2ASRD5A2MAOBMAPT | |
| SCHEMBL31419920 | 0.67 | PARK7 (0.54) | KDM4CMEN1KMT2AMAOBHRH3 | |
| SCHEMBL29289495 | 0.67 | PARK7 (0.54) | KDM4CMEN1KMT2AMAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192770-A | Antiemetic, anxiolytic, cognition activator | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0490263-A1 | Alpha-oxoacetamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |