Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386316 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2F10 | |
| SCHEMBL7385706 | 0.87 | F2 (0.60) | ITGB3ITGA2BEPHX2F10PRSS1 | |
| SCHEMBL7384201 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BF10 | |
| SCHEMBL9293681 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BEPHX2F10PRSS1 | |
| SCHEMBL7384435 | 0.83 | ITGB3 (0.71) | ITGB3ITGA2BEPHX2 | |
| SCHEMBL7383400 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BF10 | |
| SCHEMBL7383847 | 0.81 | EPHX2 (0.57) | ITGB3ITGA2BEPHX2CCR3 | |
| SCHEMBL7385683 | 0.81 | EPHX2 (0.54) | ITGB3ITGA2BEPHX2CCR3THRB | |
| SCHEMBL9386338 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2BF10 | |
| SCHEMBL7384465 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | claimed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | claimed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | claimed |
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |