Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425047 | 0.83 | ITGB1 (0.54) | ITGB1ITGA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7430020 | 0.83 | ITGB1 (0.49) | ITGB1ITGA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7429200 | 0.82 | ITGB1 (0.53) | ITGB1ITGA4SMN1; SMN2KMT2A | |
| SCHEMBL7396001 | 0.81 | SMN1; SMN2 (0.49) | ITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL7426846 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7390925 | 0.76 | ITGB1 (0.53) | ITGB1ITGA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7392261 | 0.75 | THRB (0.47) | ITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7390959 | 0.74 | ITGB1 (0.44) | ITGB1ITGA4KMT2AMEN1CCR8 | |
| SCHEMBL7431427 | 0.73 | ITGB1 (0.53) | ITGB1ITGA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7383245 | 0.73 | ITGB1 (0.49) | ITGB1ITGA4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |