Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK13 | Q9HB14 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394378 | 0.92 | ALDH1A1 (0.63) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7394081 | 0.90 | TP53 (0.54) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7385426 | 0.88 | KDM4E (0.52) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7392863 | 0.85 | KDM4E (0.52) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7387710 | 0.85 | ALDH1A1 (0.54) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7393927 | 0.83 | MAPT (0.55) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7391911 | 0.83 | CFTR (0.53) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7394556 | 0.82 | TP53 (0.64) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL7394475 | 0.82 | TP53 (0.66) | ALDH1A1TP53TSHRHTTLMNA | |
| SCHEMBL7396158 | 0.82 | TSHR (0.58) | ALDH1A1PDE6DALDH2ALDH3A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130333-A | VISION DEFECTS; CARDIOVASCULAR DISORDERS | MONSANTO COMPANY (US) | 2000-10-10 | — | — | US | disclosed |