Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116777 | 1.00 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL114956 | 1.00 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL118315 | 1.00 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL116959 | 0.93 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL116449 | 0.93 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL738406 | 0.93 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL115550 | 0.93 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL28988001 | 0.91 | CES2 (0.42) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL736636 | 0.87 | CES2 (0.52) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL114395 | 0.87 | CES2 (0.52) | CES2CES1MEN1FAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658508-B2 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2024-06-19 | — | — | EP | disclosed |
| EP-2658508-B1 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-2560606-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2560608-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-2346481-B1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| EP-2377513-B1 | Colouring composition | KAO GERMANY GMBH (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2346480-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2016-01-06 | — | — | EP | disclosed |
| US-8795391-B2 | Colouring composition | KAO GERMANY GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8673022-B2 | Colouring composition | KAO GERMANY GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8668746-B2 | Two-part hair colouring composition | KAO GERMANY GMBH (DE) | 2014-03-11 | — | — | US | disclosed |
| EP-2377511-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-10-19 | — | — | EP | disclosed |
| EP-2377513-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110240052-A1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH | 2011-10-06 | — | — | US | disclosed |
| US-20110197912-A1 | COLORING COMPOSITION | KPSS-KAO PROFESSIONAL SAL SERVICES GMBH | 2011-08-18 | — | — | US | disclosed |
| EP-2346481-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-2346480-A2 | COLOURING COMPOSITION | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046077-A2 | COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046080-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177204-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177205-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110197912-A1 | COLORING COMPOSITION | KRT18, POLL, POLQ | CES2 3339/4885CES1 3146/4885MEN1 2578/4885 |
| US-20110240052-A1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | POLR1C, DRD3, DRD4 | CES2 1784/4885CES1 2086/4885MEN1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.