Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604859 | 0.89 | GRM5 (0.62) | GRM5MEN1KMT2AALDH1A1ADORA2A | |
| SCHEMBL30792888 | 0.89 | GRM5 (0.62) | GRM5MEN1KMT2AALDH1A1ADORA2A | |
| SCHEMBL7334559 | 0.81 | GRM5 (0.58) | GRM5MEN1KMT2A | |
| SCHEMBL30758580 | 0.78 | MEN1 (0.67) | MEN1KMT2AALDH1A1ADORA2AGAA | |
| SCHEMBL30777591 | 0.78 | MEN1 (0.67) | MEN1KMT2AALDH1A1ADORA2AGAA | |
| SCHEMBL259386 | 0.78 | MEN1 (0.67) | MEN1KMT2AALDH1A1ADORA2AGAA | |
| SCHEMBL325212 | 0.77 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1ADORA2AGAA | |
| SCHEMBL30472945 | 0.77 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1ADORA2AGAA | |
| SCHEMBL4101226 | 0.74 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL22129204 | 0.74 | HTT (0.57) | GRM5MEN1KMT2AALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0778839-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006849-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |