Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380211 | 0.90 | AGTR2 (0.41) | AGTR2AGTR1PPARG | |
| SCHEMBL7381561 | 0.86 | AGTR2 (0.42) | AGTR2AGTR1 | |
| SCHEMBL7387716 | 0.85 | AGTR2 (0.45) | AGTR2AGTR1 | |
| SCHEMBL9662128 | 0.85 | AGTR1 (0.51) | AGTR2AGTR1 | |
| SCHEMBL7387246 | 0.83 | AGTR2 (0.56) | AGTR2AGTR1 | |
| SCHEMBL7384595 | 0.82 | AGTR1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL7386246 | 0.81 | AGTR1 (0.45) | AGTR2AGTR1PPARG | |
| SCHEMBL7387098 | 0.80 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL7382796 | 0.79 | AGTR2 (0.56) | AGTR2AGTR1 | |
| SCHEMBL7389075 | 0.78 | PPARG (0.52) | AGTR2AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177074-A | Heterocyclic nitrogen compounds used to treat hypertension, cognitive dysfunction, anxiety or depression | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0513979-A1 | Angiotensin II antagonists incorporating a substituted thiophene or furan | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |