Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.64 |
| ▸ | MMP13 | P45452 | 9/20 | 0.64 |
| ▸ | MMP3 | P08254 | 8/20 | 0.64 |
| ▸ | MMP9 | P14780 | 7/20 | 0.64 |
| ▸ | MMP1 | P03956 | 6/20 | 0.64 |
| ▸ | MMP7 | P09237 | 3/20 | 0.64 |
| ▸ | MMP8 | P22894 | 2/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733789 | 1.00 | MMP2 (0.64) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6768375 | 1.00 | MMP2 (0.64) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6742257 | 0.93 | MMP13 (0.58) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6738347 | 0.89 | MMP2 (0.67) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6736584 | 0.89 | MMP2 (0.67) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6732456 | 0.86 | MMP13 (0.63) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6738197 | 0.86 | MMP13 (0.63) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6741519 | 0.84 | MMP2 (0.60) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL6738036 | 0.84 | MMP2 (0.60) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7391332 | 0.83 | MMP13 (0.54) | MMP2MMP13MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224171-A1 | BETA DISUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-07-24 | — | — | EP | claimed |
| WO-2001027084-A1 | BETA DISUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | claimed |