Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388218 | 0.92 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2HTR1ASLC6A2 | |
| SCHEMBL7392283 | 0.90 | CCR3 (0.59) | KDM4EALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL7384798 | 0.89 | CCR3 (0.58) | KDM4EALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL10722398 | 0.84 | HPGD (0.67) | HPGDCD274KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7388016 | 0.82 | ALDH1A1 (0.69) | KDM4EALDH1A1SMN1; SMN2HTR1ASLC6A2 | |
| SCHEMBL1381550 | 0.81 | ALDH1A1 (0.70) | HPGDCD274ALDH1A1 | |
| SCHEMBL7386299 | 0.81 | CCR3 (0.65) | KDM4EALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL4502913 | 0.80 | CYP1A2 (0.73) | HPGDCD274KDM4EALDH1A1 | |
| SCHEMBL7395919 | 0.80 | KMT2A (0.68) | EPHX2MAPT | |
| SCHEMBL7381097 | 0.80 | CCR3 (0.64) | KDM4EALDH1A1SMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |