SCHEMBL7387255

SCHEMBL7387255

S=C=Nc1cc(N=C=S)cc(N=C=S)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.55
P2RY6 Q15077 4/20 0.48
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PNMT P11086 1/20 0.38
CYP3A4 P08684 5/20 0.36
HSD17B10 Q99714 4/20 0.36
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
USP2 O75604 2/20 0.36
LTA P01374 2/20 0.36
P2RX3 P56373 2/20 0.36
RAD51 Q06609 2/20 0.36
RAD1 O60671 1/20 0.36
ALOX15 P16050 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483888 0.82 MIF (0.67) MIFP2RY6CA1CA2PNMT
SCHEMBL7390143 0.82 MIF (0.41) MIFP2RY6CA1CA2PNMT
SCHEMBL7387579 0.80 P2RY6 (0.45) MIFP2RY6CA1CA2PNMT
SCHEMBL9963471 0.80 MIF (0.39) MIFP2RY6CA1CA2PNMT
SCHEMBL11053294 0.80 MIF (0.44) MIFP2RY6CA1CA2PNMT
SCHEMBL2824472 0.80 MIF (0.44) MIFP2RY6CA1CA2PNMT
SCHEMBL9425791 0.80 MIF (0.44) MIFP2RY6CA1CA2PNMT
SCHEMBL1457225 0.80 MIF (0.44) MIFP2RY6CA1CA2PNMT
SCHEMBL1020699 0.80 MIF (0.44) MIFP2RY6CA1CA2PNMT
Bitoscanate SCHEMBL157128 0.79 MIF (0.72) MIFP2RY6CA1CA2PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US claimed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US claimed
US-20230317919-A1 DEPOSITION OF FILMS ONTO BATTERY MATERIAL POWDERS CORESHELL TECHNOLOGIES, INC. 2023-10-05 US disclosed
EP-4205193-A1 DEPOSITION OF FILMS ONTO BATTERY MATERIAL POWDERS Coreshell Technologies, Inc. (US) 2023-07-05 EP disclosed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US disclosed
WO-2022047268-A1 DEPOSITION OF FILMS ONTO BATTERY MATERIAL POWDERS CORESHELL TECHNOLOGIES, INC. (US) 2022-03-03 WO disclosed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US disclosed
US-20150344613-A1 POLYTHIOUREA COMPOSITIONS AND METHODS OF USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-03 US disclosed
US-5310916-A Trifunctional agents useful as irreversible inhibitors of A1-adenosine receptors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344613-A1 POLYTHIOUREA COMPOSITIONS AND METHODS OF USE PNMT, SRM, PUF60 MIF 2203/4885P2RY6 3010/4885CA1 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.