Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | HK1 | P19367 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952755 | 0.85 | ACHE (0.67) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL15746282 | 0.78 | ACHE (1.00) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL5952380 | 0.77 | ACHE (0.68) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL7383485 | 0.76 | ALDH1A1 (0.44) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL5952366 | 0.75 | ACHE (0.71) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL5952549 | 0.74 | ACHE (0.60) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL5951706 | 0.74 | ACHE (0.60) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL13115609 | 0.74 | ACHE (0.68) | ACHELMNAMAPTCYP19A1STAT3 | |
| SCHEMBL5951755 | 0.74 | ACHE (0.69) | ACHEKDM4ELMNAPOLBMAPT | |
| SCHEMBL5951821 | 0.73 | ACHE (0.58) | ACHEKDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504104-A | TREATING INFECTIONS OR DISEASES CAUSED BY RETROVIRUSES, SUCH AS HIV AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-02 | — | — | US | disclosed |