Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497382 | 0.93 | CNR1 (0.48) | SRD5A2LTB4RLTB4R2MEN1NPC1 | |
| SCHEMBL27732143 | 0.83 | CNR1 (0.49) | SRD5A2LTB4RLTB4R2MEN1NPC1 | |
| SCHEMBL5894096 | 0.81 | PLA2G2A (0.56) | LTB4RLTB4R2PLA2G2APPARGPPARD | |
| SCHEMBL2433126 | 0.81 | LTB4R (0.55) | SRD5A2LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL2085650 | 0.81 | CNR1 (0.47) | SRD5A2LTB4RLTB4R2MEN1NPC1 | |
| SCHEMBL7384942 | 0.80 | ABCG2 (0.56) | NR4A2 | |
| SCHEMBL6087231 | 0.80 | PARP10 (0.49) | SRD5A2LTB4RLTB4R2MEN1NPC1 | |
| SCHEMBL28995408 | 0.78 | SRD5A2 (0.51) | SRD5A2LTB4RLTB4R2MEN1NPC1 | |
| SCHEMBL2434205 | 0.78 | NR4A2 (0.58) | SRD5A2LTB4RLTB4R2NPC1RAB9A | |
| SCHEMBL3203412 | 0.78 | SERPINE1 (0.64) | LTB4RLTB4R2MEN1KMT2APLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192770-A | Antiemetic, anxiolytic, cognition activator | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0490263-A1 | Alpha-oxoacetamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |