Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394590 | 0.85 | TPMT (0.41) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7415324 | 0.77 | HSD17B10 (0.42) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7307695 | 0.72 | HSD17B10 (0.41) | LMNAMEN1KMT2AALDH1A1ABL1 | |
| SCHEMBL27345965 | 0.67 | KDM4E (0.43) | LMNAMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL18700971 | 0.66 | IKBKB (0.51) | LMNAMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7415790 | 0.66 | PARP1 (0.43) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL7318609 | 0.66 | HSD17B10 (0.36) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7394466 | 0.65 | LMNA (0.41) | LMNAMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL11039143 | 0.64 | KDM4E (0.49) | LMNAMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL18700959 | 0.64 | GAA (0.42) | LMNAMEN1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539125-A | 1-azabicyclo[3.3.0]octan derivative, salt thereof, process for the preparation of same and use thereof as hypermotility agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0691340-A1 | 1-Azabicyclo 3.3.0 octan derivative, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |