Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.63 |
| ▸ | F2 | P00734 | 6/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386374 | 0.89 | PRSS1 (0.56) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL7388981 | 0.89 | PRSS1 (0.70) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL7389290 | 0.86 | PRSS1 (0.56) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL7392973 | 0.82 | ALDH1A1 (0.63) | PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14599541 | 0.81 | PRSS1 (0.68) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL7390198 | 0.79 | PRSS1 (0.48) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL428920 | 0.79 | PRSS1 (1.00) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL7381007 | 0.78 | NPC1 (0.59) | MAPK1 | |
| Hydrochloric Acid SCHEMBL23541004 | 0.77 | PRSS1 (0.96) | PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL427173 | 0.77 | PRSS1 (0.96) | PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |