Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.56 |
| ▸ | F2 | P00734 | 8/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388981 | 0.89 | PRSS1 (0.70) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL7387777 | 0.86 | PRSS1 (0.63) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL7386374 | 0.86 | PRSS1 (0.56) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL11545859 | 0.82 | NR4A2 (0.64) | CYP1A2 | |
| SCHEMBL14599541 | 0.81 | PRSS1 (0.68) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL7390198 | 0.79 | PRSS1 (0.48) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL6938286 | 0.77 | CYP1A2 (0.63) | CYP1A2 | |
| SCHEMBL7381578 | 0.76 | F2 (0.58) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL7387529 | 0.75 | ALDH1A1 (0.55) | PRSS1F2PLGPRSS2PRSS3 | |
| SCHEMBL12348321 | 0.74 | PRSS1 (0.77) | PRSS1F2PLGPRSS2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |