Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.53 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | F7 | P08709 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388004 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BF2KMT2AF10 | |
| SCHEMBL7387014 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BF2KMT2AF10 | |
| SCHEMBL7387467 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BF2F7 | |
| SCHEMBL7387474 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BF2F7 | |
| SCHEMBL7388209 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BF2KMT2AF10 | |
| SCHEMBL7387186 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BF2KMT2AF10 | |
| SCHEMBL7387179 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BF2KMT2AF10 | |
| SCHEMBL7387361 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BF2F10F7 | |
| SCHEMBL9394443 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BF2F10F7 | |
| SCHEMBL7389396 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BF2KMT2AF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |