Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.59 |
| ▸ | F7 | P08709 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390820 | 0.90 | ITGB3 (0.74) | ITGB3ITGA2BF7F2 | |
| SCHEMBL9389702 | 0.90 | ITGB3 (0.74) | ITGB3ITGA2BF7F2 | |
| SCHEMBL7389396 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BF7F2KMT2A | |
| SCHEMBL6984596 | 0.88 | ITGB3 (0.76) | ITGB3ITGA2BF2 | |
| SCHEMBL7387014 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL7388004 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL7387994 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL9394443 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL7387361 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL7388211 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BF7F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |