Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389213 | 0.85 | NPC1 (0.54) | NPC1RAB9ATSHRHRH2HRH1 | |
| SCHEMBL7392918 | 0.83 | NPC1 (0.56) | NPC1RAB9ATSHRHRH2HRH1 | |
| SCHEMBL10541477 | 0.83 | ALPL (0.64) | ALPLALPGKDM4EL3MBTL1GAA | |
| SCHEMBL7391718 | 0.83 | DRD4 (0.47) | KDM4EL3MBTL1DRD4DRD3 | |
| SCHEMBL7387518 | 0.83 | DRD2 (0.50) | KDM4EL3MBTL1NPC1ALDH1A1TP53 | |
| SCHEMBL7389899 | 0.83 | DRD2 (0.57) | KDM4EL3MBTL1NPC1ALDH1A1TP53 | |
| SCHEMBL7388924 | 0.83 | DRD2 (0.50) | KDM4EL3MBTL1NPC1ALDH1A1TP53 | |
| SCHEMBL10540790 | 0.82 | ALPL (0.67) | ALPLALPGKDM4EL3MBTL1GAA | |
| SCHEMBL7389420 | 0.82 | HDAC1 (0.56) | KDM4EL3MBTL1SMN1; SMN2HTR1ADRD3 | |
| SCHEMBL7395417 | 0.81 | DRD2 (0.60) | ALDH1A1TSHRHRH2HRH1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |