SCHEMBL7388205 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	ITGB3	P05106	10/20	0.42

▸	ITGA2B	P08514	10/20	0.42

▸	F10	P00742	8/20	0.42

▸	PRSS1	P07477	9/20	0.42

▸	PRSS2	P07478	9/20	0.42

▸	PRSS3	P35030	9/20	0.42

▸	F2	P00734	1/20	0.41

▸	SIGMAR1	Q99720	7/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7392003	0.88	F10 (0.47)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7386142	0.88	ITGB3 (0.42)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7389847	0.88	ITGB3 (0.46)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7389827	0.87	TPSAB1 (0.51)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7392421	0.86	F10 (0.50)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7391303	0.86	F10 (0.45)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7383500	0.85	F10 (0.45)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7387918	0.85	F10 (0.44)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7387830	0.85	F10 (0.45)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL7383582	0.85	ITGB3 (0.47)	ITGB3ITGA2BF10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1056743-A1	BENZAMINE DERIVATIVES	MERCK PATENT GmbH (DE)	2000-12-06	—	—	EP	disclosed
WO-1999031092-A1	BENZAMINE DERIVATIVES	MERCK PATENT GMBH (DE)	1999-06-24	—	—	WO	disclosed