Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408350 | 0.87 | KMT2A (0.59) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL13939148 | 0.86 | ALDH1A1 (0.63) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL1624506 | 0.81 | KMT2A (0.66) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL27898835 | 0.81 | MAPK1 (0.73) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL7389628 | 0.79 | SIRT2 (0.54) | KMT2AMEN1GAAMAPTTDP1 | |
| SCHEMBL28172420 | 0.79 | TDP1 (0.60) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL3631346 | 0.79 | AR (0.57) | KMT2AMEN1GAAPKMALDH1A1 | |
| SCHEMBL27226016 | 0.79 | MAPK1 (0.62) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL15082040 | 0.78 | L3MBTL1 (0.68) | KMT2AMEN1MAPK1GAAMAPT | |
| SCHEMBL27226881 | 0.78 | MAPT (0.69) | KMT2AMEN1MAPK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |