Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2RA | P01589 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390912 | 0.89 | GAA (0.40) | IL2RAALBIL2F2CCR5 | |
| SCHEMBL7394950 | 0.88 | KMT2A (0.38) | IL2RAALBIL2KMT2ACCR1 | |
| Hydrochloric Acid SCHEMBL9003252 | 0.88 | GAA (0.40) | IL2RAALBIL2F2CCR5 | |
| SCHEMBL7397245 | 0.88 | CASP1 (0.41) | IL2RAALBIL2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL9003087 | 0.88 | KMT2A (0.37) | IL2RAALBIL2KMT2ACCR1 | |
| Hydrochloric Acid SCHEMBL9002984 | 0.87 | CASP1 (0.41) | IL2RAALBIL2F10PRSS1 | |
| SCHEMBL7392735 | 0.87 | KMT2A (0.40) | IL2RAALBIL2CCR5F10 | |
| Hydrochloric Acid SCHEMBL9002527 | 0.86 | KMT2A (0.40) | IL2RAALBIL2F2CCR5 | |
| SCHEMBL7386668 | 0.84 | ITGB3 (0.34) | IL2RAALBIL2F2PRSS1 | |
| SCHEMBL9003091 | 0.84 | F2 (0.53) | IL2RAALBIL2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0641779-A1 | Novel 1-amidinopiperdines and 4-amidinomorpholines as aggregation inhibitions | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |