Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343186 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL11019424 | 0.81 | — | — | |
| SCHEMBL8006196 | 0.79 | — | — | |
| SCHEMBL10840657 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6382870 | 0.79 | — | — | |
| SCHEMBL1958756 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL3673 | 0.78 | — | — | |
| SCHEMBL1332089 | 0.78 | — | — | |
| SCHEMBL2336864 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL9993863 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SOAT1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008844-A1 | THIAZOLE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE-IV | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0045837-B1 | REACTIVE DERIVATIVES OF 3-OXA-BICYCLO(4.3.0)-NON-1-ENE-9-ONE, PROCESS FOR THEIR PREPARATION AND THEIR USE | Dr. Willmar Schwabe GmbH & Co. (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0045837-A1 | Reactive derivatives of 3-oxa-bicyclo(4.3.0)-non-1-ene-9-one, process for their preparation and their use | Dr. Willmar Schwabe GmbH & Co. (DE) | 1982-02-17 | — | — | EP | disclosed |