Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 8/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 7/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176254 | 0.91 | L3MBTL1 (0.41) | L3MBTL1CCKARSTING1 | |
| SCHEMBL8180219 | 0.90 | SERPINE1 (0.42) | SERPINE1L3MBTL1ICAM1SELECCNC | |
| SCHEMBL8176541 | 0.90 | SERPINE1 (0.40) | SERPINE1L3MBTL1STING1ICAM1SELE | |
| SCHEMBL7394624 | 0.76 | STING1 (0.50) | SERPINE1L3MBTL1STING1 | |
| SCHEMBL7395401 | 0.75 | L3MBTL1 (0.51) | SERPINE1L3MBTL1STING1ICAM1SELE | |
| SCHEMBL7431728 | 0.73 | ALDH1A1 (0.46) | SERPINE1 | |
| SCHEMBL7395385 | 0.73 | L3MBTL1 (0.46) | SERPINE1L3MBTL1STING1ICAM1SELE | |
| SCHEMBL7392946 | 0.72 | L3MBTL1 (0.43) | SERPINE1L3MBTL1STING1ICAM1SELE | |
| SCHEMBL7394439 | 0.72 | L3MBTL1 (0.43) | SERPINE1L3MBTL1STING1ICAM1SELE | |
| SCHEMBL8167415 | 0.72 | L3MBTL1 (0.44) | SERPINE1L3MBTL1STING1ICAM1SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955299-B1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-13 | — | — | EP | disclosed |
| EP-0955299-A1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-11-10 | — | — | EP | disclosed |