Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.40 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387009 | 0.92 | F10 (0.38) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7391175 | 0.92 | HRH3 (0.41) | F10F2ACACB | |
| SCHEMBL7384317 | 0.91 | GPR119 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7388567 | 0.84 | F10 (0.56) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7390197 | 0.81 | TP53 (0.35) | F10F2CYP11B1CYP11B2 | |
| SCHEMBL7379683 | 0.79 | ESR1 (0.37) | F10F2 | |
| SCHEMBL7379072 | 0.79 | GPR119 (0.37) | F10F2GPR119 | |
| SCHEMBL7385010 | 0.78 | GPR119 (0.37) | GPR119 | |
| SCHEMBL7392679 | 0.78 | GPR119 (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7386798 | 0.78 | GPR119 (0.50) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |