SCHEMBL738858

SCHEMBL738858

CCCCCCCCCCCCCCCCCCCCCC(=O)C(CC)NCC(O)CO

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
LMNA P02545 1/20 0.46
CES2 O00748 1/20 0.43
FAAH O00519 1/20 0.41
MAPK1 P28482 1/20 0.41
HSP90AA1 P07900 1/20 0.41
DGKA P23743 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115573 1.00 MEN1 (0.46) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL116561 1.00 MEN1 (0.46) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL3837639 0.89 FFAR4 (0.46) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL116650 0.85 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL737893 0.85 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL115181 0.85 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL739424 0.79 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL116808 0.79 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL117849 0.79 CES2 (0.47) MEN1KMT2ACES2FAAHMAPK1
SCHEMBL736192 0.78 MEN1 (0.52) MEN1KMT2ACES2FAAHMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658508-B2 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2024-06-19 EP disclosed
EP-2658508-B1 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2021-06-16 EP disclosed
EP-2560606-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-08-23 EP disclosed
EP-2560608-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-04-05 EP disclosed
EP-2346481-B1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-08-31 EP disclosed
EP-2377513-B1 Colouring composition KAO GERMANY GMBH (DE) 2016-03-30 EP disclosed
EP-2346480-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2016-01-06 EP disclosed
US-8795391-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-08-05 US disclosed
US-8673022-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-03-18 US disclosed
US-8668746-B2 Two-part hair colouring composition KAO GERMANY GMBH (DE) 2014-03-11 US disclosed
EP-2377511-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 EP disclosed
EP-2377513-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 EP disclosed
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH 2011-10-06 US disclosed
US-20110197912-A1 COLORING COMPOSITION KPSS-KAO PROFESSIONAL SAL SERVICES GMBH 2011-08-18 US disclosed
EP-2346481-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 EP disclosed
EP-2346480-A2 COLOURING COMPOSITION KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 EP disclosed
WO-2010046077-A2 COLOURING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
WO-2010046080-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
EP-2177205-A1 Composition for the permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
EP-2177204-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110197912-A1 COLORING COMPOSITION KRT18, POLL, POLQ MEN1 2578/4885KMT2A 758/4885KDM4E 125/4885
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR POLR1C, DRD3, DRD4 MEN1 430/4885KMT2A 1457/4885KDM4E 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.