Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391000 | 0.80 | ELANE (0.43) | IDO1ALDH1A1MAPTCHRNA1CHRNG | |
| SCHEMBL7388034 | 0.77 | ALDH1A1 (0.42) | IDO1ALDH1A1MAPTCHRNA1CHRNG | |
| SCHEMBL7391436 | 0.77 | TDP1 (0.44) | IDO1ALDH1A1MAPTCHRNA1CHRNG | |
| SCHEMBL7398567 | 0.76 | IDO1 (0.36) | IDO1ALDH1A1MAPTCHRNA1CHRNG | |
| SCHEMBL7397588 | 0.76 | ELANE (0.45) | ALDH1A1MMP12CYP11B2 | |
| SCHEMBL7393339 | 0.76 | IDO1 (0.36) | IDO1ALDH1A1MAPTCHRNA1CHRNG | |
| SCHEMBL7395287 | 0.72 | ELANE (0.42) | IDO1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL7394217 | 0.72 | KDM4E (0.41) | IDO1ALDH1A1MAPTLTKGSK3B | |
| SCHEMBL7401354 | 0.72 | LMNA (0.44) | IDO1ALDH1A1MAPTMMP12TDP1 | |
| SCHEMBL7395901 | 0.72 | ALDH1A1 (0.45) | IDO1ALDH1A1MAPTCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863947-A | Phenylglycine derivatives useful for treating disorders of the central nervous system | ELI LILLY AND COMPANY LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |
| EP-0807621-A1 | Derivatives of phenylglycine and use thereof as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1997-11-19 | — | — | EP | disclosed |