Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383400 | 0.87 | ITGB3 (0.55) | F10ITGB3ITGA2BST14 | |
| SCHEMBL7383870 | 0.87 | F2 (0.49) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7385655 | 0.86 | ITGB3 (0.57) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7385706 | 0.84 | F2 (0.60) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7384715 | 0.83 | ITGB3 (0.59) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7388769 | 0.82 | ITGB3 (0.44) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7387496 | 0.80 | ITGB3 (0.54) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL8776989 | 0.79 | F2 (0.49) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7386035 | 0.78 | F2 (0.50) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL9390323 | 0.77 | ITGB3 (0.51) | F2F10PRSS1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |