Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721971 | 0.88 | ITGB3 (0.58) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7416760 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BF10KMT2APRSS1 | |
| SCHEMBL7385706 | 0.82 | F2 (0.60) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7388772 | 0.79 | F2 (0.51) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7385708 | 0.78 | TSHR (0.53) | TSHRKLKB1POLBKMT2A | |
| SCHEMBL7384711 | 0.78 | F10 (0.42) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7388769 | 0.78 | ITGB3 (0.44) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL9435428 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BPOLB | |
| SCHEMBL7384715 | 0.77 | ITGB3 (0.59) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7383870 | 0.76 | F2 (0.49) | F2ITGB3ITGA2BF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659193-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1997-12-10 | — | — | EP | claimed |