Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389626 | 0.84 | CACNA1B (0.67) | EPHX2CTSSGAACACNA1BCAPN1 | |
| SCHEMBL7391081 | 0.84 | CTSS (0.59) | CTSSGAACACNA1B | |
| SCHEMBL7422164 | 0.76 | CACNA1B (0.61) | CTSSGAACACNA1BCAPN1 | |
| SCHEMBL7393887 | 0.76 | CACNA1B (0.57) | GAACNR1CNR2CACNA1B | |
| SCHEMBL7429201 | 0.75 | CACNA1B (0.66) | CTSSGAACACNA1BCAPN1 | |
| SCHEMBL7341276 | 0.74 | CACNA1B (0.58) | CTSSCACNA1B | |
| SCHEMBL7343417 | 0.74 | CACNA1B (0.58) | CTSSCACNA1B | |
| SCHEMBL7037594 | 0.74 | CACNA1B (0.60) | CTSSGAACACNA1B | |
| SCHEMBL7037597 | 0.74 | CACNA1B (0.60) | CTSSGAACACNA1B | |
| SCHEMBL7342473 | 0.74 | CACNA1B (0.60) | CTSSGAACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |