Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429201 | 0.91 | CACNA1B (0.66) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7422164 | 0.88 | CACNA1B (0.61) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7391849 | 0.86 | CACNA1B (0.52) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7388947 | 0.84 | EPHX2 (0.64) | CACNA1BCAPN1EPHX2CTSSGAA | |
| SCHEMBL7429418 | 0.83 | MAPK1 (0.50) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL25531422 | 0.81 | CACNA1B (1.00) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL11932026 | 0.81 | CACNA1B (1.00) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7389138 | 0.78 | CACNA1B (0.69) | CACNA1BCAPN1CTSSCTSL | |
| SCHEMBL7389141 | 0.78 | CACNA1B (0.69) | CACNA1BCAPN1CTSSCTSL | |
| SCHEMBL7662096 | 0.75 | CACNA1B (0.72) | CACNA1BFAAHCYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |