Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387697 | 0.87 | PDE4A (0.49) | PDE4APDE4DPDE4BPDE4CS1PR1 | |
| SCHEMBL7389100 | 0.86 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CS1PR1 | |
| SCHEMBL7389939 | 0.86 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4CS1PR1 | |
| SCHEMBL7321981 | 0.84 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CS1PR1 | |
| SCHEMBL7390717 | 0.82 | PDE4A (0.53) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7389555 | 0.82 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4CS1PR1 | |
| SCHEMBL7387866 | 0.75 | PDE4A (0.49) | PDE4APDE4DPDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7385717 | 0.74 | PDE4D (0.50) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7334529 | 0.73 | PDE4B (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8688517 | 0.72 | PDE4A (0.50) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780477-A | Trisubstituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-14 | — | — | US | claimed |
| US-5780477-A | Trisubstituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |