Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213702 | 0.85 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DAR | |
| SCHEMBL3317724 | 0.68 | POLB (0.55) | ARSMN1; SMN2TSHRATMNPSR1 | |
| SCHEMBL1542104 | 0.68 | SMN1; SMN2 (0.55) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL9675030 | 0.67 | PARP1 (0.53) | SMN1; SMN2TSHRATMNPSR1MAPK1 | |
| SCHEMBL27741179 | 0.67 | SMN1; SMN2 (0.47) | PDE4APDE4BPDE4CPDE4DAR | |
| SCHEMBL6236381 | 0.65 | LMNA (0.53) | ARSMN1; SMN2TSHRATMNPSR1 | |
| SCHEMBL3312900 | 0.65 | SMN1; SMN2 (0.49) | ARSMN1; SMN2TSHRGAAMAPT | |
| SCHEMBL1966860 | 0.65 | CNR1 (0.59) | SMN1; SMN2CYP2C19CYP3A4GAAALDH1A1 | |
| SCHEMBL31134461 | 0.65 | CNR1 (0.59) | SMN1; SMN2CYP2C19CYP3A4GAAALDH1A1 | |
| SCHEMBL1789261 | 0.64 | ATM (0.50) | ARGAAMAPTATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934933-A1 | Phthalazinones | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-08-11 | — | — | EP | disclosed |