Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181098 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL4401205 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL12181105 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBATMTSHR | |
| SCHEMBL372115 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBATMTSHR | |
| SCHEMBL372116 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBATMTSHR | |
| SCHEMBL10602801 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBATMMEN1 | |
| SCHEMBL10779381 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBL3MBTL1THRB | |
| SCHEMBL10779374 | 0.67 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBL3MBTL1THRB | |
| SCHEMBL23136474 | 0.67 | LMNA (0.32) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL23136473 | 0.67 | LMNA (0.32) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |