Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24165240 | 0.74 | ELANE (0.36) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL11512609 | 0.73 | AGPAT2 (0.42) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL2912166 | 0.65 | POLB (0.56) | KDM4EGAAGLAMAPTALDH1A1 | |
| SCHEMBL5469722 | 0.64 | ALDH1A1 (0.49) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL13342884 | 0.63 | KDM4E (0.61) | KDM4EGAAGLAMAPTALDH1A1 | |
| SCHEMBL3688841 | 0.62 | LMNA (0.50) | KDM4EGAAGLAMAPTALDH1A1 | |
| SCHEMBL27298985 | 0.62 | POLB (0.44) | KDM4EGAAGLAMAPTALDH1A1 | |
| SCHEMBL27523005 | 0.59 | HTT (0.51) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL24165265 | 0.59 | ELANE (0.35) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL28575486 | 0.59 | PIK3CG (0.31) | GLAMAPTALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |