Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390351 | 1.00 | HRH3 (0.41) | HRH3DGAT1F10P2RY14USP30 | |
| SCHEMBL7392094 | 0.90 | POLB (0.41) | DGAT1F10ALDH1A1PDK2 | |
| SCHEMBL7392091 | 0.90 | POLB (0.41) | DGAT1F10ALDH1A1PDK2 | |
| SCHEMBL8417020 | 0.84 | RORC (0.38) | HRH3F10USP30ALDH1A1PDK2 | |
| SCHEMBL8417022 | 0.84 | RORC (0.38) | HRH3F10USP30ALDH1A1PDK2 | |
| Hydrochloric Acid SCHEMBL7390541 | 0.82 | HRH3 (0.43) | HRH3ALDH1A1NAMPTBTK | |
| SCHEMBL8413959 | 0.80 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL8413955 | 0.80 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL7356039 | 0.80 | HRH3 (0.37) | HRH3DGAT1P2RY14ALDH1A1KDM1A | |
| SCHEMBL7356046 | 0.80 | HRH3 (0.37) | HRH3DGAT1P2RY14ALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |