Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392094 | 1.00 | POLB (0.41) | POLBALDH1A1MAPTHSD17B10LGMN | |
| SCHEMBL7390351 | 0.90 | HRH3 (0.41) | ALDH1A1DGAT1F10PDK2 | |
| SCHEMBL7390348 | 0.90 | HRH3 (0.41) | ALDH1A1DGAT1F10PDK2 | |
| SCHEMBL7390889 | 0.84 | KHK (0.41) | ALDH1A1MAPTLGMNKDM4EF10 | |
| SCHEMBL7390891 | 0.84 | KHK (0.41) | ALDH1A1MAPTLGMNKDM4EF10 | |
| Hydrochloric Acid SCHEMBL7391597 | 0.83 | KHK (0.41) | ALDH1A1MAPTLGMNKDM4EF10 | |
| SCHEMBL7391329 | 0.82 | FDFT1 (0.44) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL8417022 | 0.74 | RORC (0.38) | ALDH1A1MAPTF10PDK2 | |
| SCHEMBL8417020 | 0.74 | RORC (0.38) | ALDH1A1MAPTF10PDK2 | |
| SCHEMBL8413955 | 0.74 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |