Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391297 | 0.94 | CACNA1B (0.41) | CACNA1BCCR3CHRM2CHRM1KDM2B | |
| SCHEMBL7382031 | 0.89 | CACNA1B (0.40) | CACNA1BKDM2BHRH3KCNH2 | |
| SCHEMBL7390855 | 0.84 | CACNA1B (0.44) | CACNA1BKDM2B | |
| SCHEMBL7421570 | 0.83 | CACNA1B (0.43) | CACNA1BHRH3 | |
| SCHEMBL7390792 | 0.81 | CACNA1B (0.42) | CACNA1BHRH3 | |
| SCHEMBL7429335 | 0.81 | CACNA1B (0.52) | CACNA1B | |
| SCHEMBL7391056 | 0.80 | CACNA1B (0.43) | CACNA1B | |
| SCHEMBL7380663 | 0.80 | CACNA1B (0.45) | CACNA1B | |
| SCHEMBL7387300 | 0.78 | CACNA1B (0.60) | CACNA1B | |
| SCHEMBL7387556 | 0.78 | CACNA1B (0.42) | CACNA1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251919-B1 | ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN | WARNER-LAMBERT | 2001-06-26 | — | — | US | claimed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |