Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 4/20 | 0.41 |
| ▸ | LGMN | Q99538 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390889 | 1.00 | KHK (0.41) | KHKLGMNMAPTALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7391597 | 0.99 | KHK (0.41) | KHKLGMNMAPTALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7390541 | 0.88 | HRH3 (0.43) | KHKMAPTALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL7393664 | 0.86 | KHK (0.38) | KHKPARP1 | |
| SCHEMBL7391636 | 0.84 | KHK (0.44) | KHKF10PARP1 | |
| SCHEMBL7391632 | 0.84 | KHK (0.44) | KHKF10PARP1 | |
| SCHEMBL7392091 | 0.84 | POLB (0.41) | LGMNMAPTALDH1A1L3MBTL1F10 | |
| SCHEMBL7392094 | 0.84 | POLB (0.41) | LGMNMAPTALDH1A1L3MBTL1F10 | |
| SCHEMBL7385478 | 0.83 | LGMN (0.41) | KHKLGMNMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7385472 | 0.83 | LGMN (0.41) | KHKLGMNMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |