Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391096 | 1.00 | CD44 (0.34) | CD44HTR2CHTR2AADRA2APNMT | |
| SCHEMBL7797306 | 0.77 | MEN1 (0.36) | CD44ADRA2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL7902293 | 0.75 | CD44 (0.35) | CD44KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7903478 | 0.74 | PNMT (0.31) | ADRA2APNMTADRA2BADRA2C | |
| SCHEMBL9539813 | 0.74 | PNMT (0.43) | ADRA2APNMTADRA2BADRA2CALDH1A1 | |
| SCHEMBL9539807 | 0.74 | PNMT (0.43) | ADRA2APNMTADRA2BADRA2CALDH1A1 | |
| SCHEMBL5068043 | 0.72 | MEN1 (0.53) | HTR2CHTR2AADRA2APNMTADRA2B | |
| SCHEMBL7237570 | 0.72 | MEN1 (0.53) | HTR2CHTR2AADRA2APNMTADRA2B | |
| SCHEMBL8844177 | 0.71 | SLC6A2 (0.33) | HTR2C | |
| SCHEMBL7908037 | 0.71 | PNMT (0.35) | HTR2CHTR2APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376156-A | Benzodiazepin derivatives, the production and use thereof | BASF AG (DE) | 2002-10-23 | — | — | CN | claimed |
| CN-1376156-A | Benzodiazepin derivatives, the production and use thereof | BASF AG (DE) | 2002-10-23 | — | — | CN | disclosed |
| US-5589476-A | TREATMENT OF NAUSEA, VOMITING AND GASTROINTESTINAL DISORDERS | SYNTHELABO (FR) | 1996-12-31 | — | — | US | disclosed |
| CN-1109471-A | Derivative of imidazol-4yl-piperidine, preparation of same and application of same in treatment | SYNTHELABO (FR) | 1995-10-04 | — | — | CN | disclosed |
| EP-0646583-A1 | Derivatives of Imidezol-4-yl piperidine, their preparation and use in therapy | SYNTHELABO (FR) | 1995-04-05 | — | — | EP | disclosed |