Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391964 | 1.00 | ACE (0.35) | ACEENPEP | |
| Amantadine SCHEMBL7395402 | 0.85 | THRB (0.33) | — | |
| Amantadine SCHEMBL7396223 | 0.85 | THRB (0.33) | — | |
| SCHEMBL7395733 | 0.83 | ACE (0.36) | ACEENPEP | |
| SCHEMBL7394256 | 0.83 | ACE (0.33) | ACEENPEP | |
| SCHEMBL7397890 | 0.83 | ACE (0.36) | ACEENPEP | |
| SCHEMBL7394255 | 0.83 | ACE (0.33) | ACEENPEP | |
| SCHEMBL7397185 | 0.83 | MME (0.35) | ACE | |
| SCHEMBL7397187 | 0.83 | MME (0.35) | ACE | |
| SCHEMBL3218131 | 0.81 | ENPEP (0.35) | ACEENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |