Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 4/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393255 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2HTTKDM4ELMNA | |
| SCHEMBL7392000 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2HTTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7385330 | 0.83 | ITGB3 (0.40) | — | |
| Hydrochloric Acid SCHEMBL7388268 | 0.83 | ITGB3 (0.40) | — | |
| SCHEMBL7385952 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2HTTCHRM4USP14 | |
| SCHEMBL7385950 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2HTTCHRM4USP14 | |
| SCHEMBL8562570 | 0.78 | DRD2 (0.35) | — | |
| SCHEMBL8562566 | 0.78 | DRD2 (0.35) | — | |
| SCHEMBL7384638 | 0.78 | HRH3 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL7392595 | 0.78 | PPARG (0.40) | CYP11B1CYP11B2HTTCHRM4USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |