Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026396 | 0.88 | — | — | |
| SCHEMBL641314 | 0.88 | — | — | |
| SCHEMBL16058143 | 0.82 | SLC6A1 (0.32) | KMT2A | |
| Hydrochloric Acid SCHEMBL23495001 | 0.80 | SLC6A1 (0.31) | KMT2A | |
| Hydrochloric Acid SCHEMBL23495000 | 0.80 | SLC6A1 (0.31) | KMT2A | |
| SCHEMBL31043764 | 0.76 | GLI1 (0.36) | GLI1 | |
| SCHEMBL31105161 | 0.69 | SLC6A1 (0.32) | KMT2A | |
| Hydrochloric Acid SCHEMBL3696745 | 0.69 | HTR6 (0.37) | KMT2A | |
| SCHEMBL19243521 | 0.68 | — | — | |
| SCHEMBL7315743 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-A1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |