Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | PRKCB | P05771 | 2/20 | 0.38 |
| ▸ | PRKCH | P24723 | 2/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392202 | 1.00 | SPHK1 (0.40) | SPHK1PRKCAPRKCDPRKCGPRKCB | |
| SCHEMBL7397347 | 0.84 | PRKCA (0.40) | PRKCAPRKCD | |
| SCHEMBL7399030 | 0.84 | PRKCA (0.40) | PRKCAPRKCD | |
| SCHEMBL7397351 | 0.84 | PRKCA (0.40) | PRKCAPRKCD | |
| SCHEMBL7399033 | 0.82 | PRKCA (0.41) | SPHK1PRKCAPRKCDPRKCGPRKCB | |
| SCHEMBL7403999 | 0.82 | PRKCA (0.41) | SPHK1PRKCAPRKCDPRKCGPRKCB | |
| SCHEMBL7398589 | 0.82 | PRKCA (0.41) | SPHK1PRKCAPRKCDPRKCGPRKCB | |
| SCHEMBL7392204 | 0.80 | PRKCA (0.36) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7398398 | 0.80 | SPHK1 (0.40) | SPHK1F2SPHK2PRSS1CTRC | |
| SCHEMBL7398536 | 0.80 | PRKCA (0.37) | PRKCAPRKCDPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |